Welcome to the National network of Advanced Proteomics Infrastructure website
NAPI is a national platform that drives progress in mass spectrometry-based proteomics across the life sciences in Norway
NAPI partners include proteomics core facilities in Oslo, Bergen, Trondheim, Tromsø and Ås, as well as research groups with a strong focus on proteomics technology development. NAPI therefore combines the proteomics expertise available across Norway, streamlining collaborations, accelerating the development of new techniques, and providing researchers in Norway access to cutting edge proteomics technology.
NAPI officially launched in 2020. On these webpages you can learn more about NAPI and its current activities, including the broad range of techniques that can be provided as services to researchers interested in performing proteomic analyses.
Research and techniques
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Protein identification
All NAPI core facilities have extensive experience in protein identification by mass spectrometry.
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Quantitative proteomics
NAPI provides state-of-the-art expertise, methods and technology in quantitative proteomics.
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Analysis of post-translational modifications (PTMs)
Post-translational modifications (PTMs) play vital roles in signaling pathways and, consequently, in regulating cell function. PTM analysis is therefore one of the most important tasks in proteomics.
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Analysis of protein complexes/protein-protein interactions
Many of the functional units that control cell function are complexes that consist of multiple proteins.
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Modomics
Epigenetic/epitranscriptomic modifications in DNA and RNA play diverse and important roles in regulating cell behaviour. The systems-wide study of such modifications is referred to as modomics.
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Metaproteomics
Metaproteomics exploits the power of high performance MS to investigate the complete set of proteins expressed by a microbial community within a particular niche.
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Data analysis/bioinformatics
One major challenge in current proteomics is efficient and reliable data analysis.